NFL icon Deion Sanders is set for emergency surgery after a blood clot, according to Pat McAfee.
The former wide receiver and defensive back needs an operation on his groin on Friday, it was revealed.
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Ex-NFL punter McAfee broke the news on his show Thursday.
And fans wished Sanders, 55, on social media after McAfee's announcement.
One said: "Praying for coach Prime."
Another commented: "Speedy recovery, Coach. Prayers."
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Earlier this month, it was revealed Sanders was facing having his foot amputated after ongoing issues.
While the head coach of Jackson State, Sanders underwent surgery to repair a dislocated toe and an inflamed nerve, per People.
Weeks later, two of his toes turned black as a result of three femoral artery clots, which could have proved fatal, along with compartment syndrome.
As a result, Sanders' left big toe and second toe were amputated.
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He explained: "They were talking about the amputation of toes.
"Then they were talking about the amputation of my leg from the knee down. Then, they were trying to ensure I had life."
During a recent meeting with his medical team, recorded for Thee Pregame Show on YouTube, he was given an update on the condition of his leg as he continues to deal with pain.
Orthopedic surgeon Dr. Ken Hunt explained: "Ordinarily, you have three arteries that are putting blood to your foot.
"After the procedures you had before, it's down to one. That one was a little bit tenuous.
"The risk of doing something here and having a problem similar to what you had before - or worse - was too high."
Sanders is one of the most iconic players in NFL history having played both wide receiver and defensive back.
He was a two-time Super Bowl champion during his career with the Atlanta Falcons, San Francisco 49ers, Dallas Cowboys, Washington Redskins and Baltimore Ravens.
Deion also balanced a Major League Baseball career at the same time - playing for the New York Yankees, Atlanta Braves, Cincinnati Reds and San Francisco Giants.
His NFL career spanned from 1989 to 2005 while he played MLB from 1989 to 2001.
Deion's famous 'Double Play' where he played a football and baseball game in the same day was the subject of an ESPN 30for30 documentary.
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He later had a career in the media as an analyst on NFL Network.
And the Hall of Famer is now a head coach for the Colorado Boulder after three years with Jackson State.